Monday, August 15, 2011

10 Things You Should Know about Tramadol


Tramadol, the generic version of Ultram is a synthetic analgesic drug. The exact mode of action of tramadol is unknown but is said to work as morphine. Tramadol binds to opioid receptors in the brain - receptors that transmit the sensation of pain throughout the body. Here are 10 things you should know about tramadol to ensure its safe use.


1 - Tramadol is prescribed to treat moderate to moderately severe pain.

Tramadol belongs to a class of drugs known as opiate agonists. First, tramadol works by changing the way the body senses pain. Some people mistakenly believe that tramadol is a NSAID (nonsteroidal anti-inflammatory drugs), but it is not.

2 - Tramadol is available in formulations for immediate release and extended release.

Tramadol may be prescribed as an immediate release tablet (50 mg.) Or as a sustained-release tablet (100, 200, or 300 mg.). The extended-release tablets are usually reserved for patients with chronic pain who require continuous, long-term treatment.

Your doctor will determine the proper dosage for you.

3 - tablets tramadol extended release should be swallowed whole, not divided, chewed or crushed.

It is important to take tramadol properly and follow the instructions on the prescription.
If taken incorrectly or in a manner that is not recommended, serious side effects and even death can result.

4 - This medication may cause dependence in some people.

Do not take more tramadol has been prescribed for you. Taking more tramadol or take more often it can cause dependence. In addition, it should not stop taking tramadol without talking to your doctor. You may experience withdrawal symptoms if stopped suddenly.
Your doctor will probably decrease your dose of tramadol gradually.

5 - Drug interactions are possible with tramadol.

Be aware of possible interactions include:

Carbamazepine reduces the effect of tramadol
Quinidine increases the concentration of tramadol by 50% to 60%
The combination of tramadol with MAO (monoamine oxidase) inhibitors or SSRIs (selective serotonin reuptake inhibitors) can cause seizures or other serious side effects.
Be sure to tell your doctor about all medications you are taking.

6 - Tramadol, when combined with other substances may increase the central nervous system and respiratory depression.

In other words, breathing may be affected or even stopped if tramadol is combined with alcohol, narcotics, anesthetics, tranquilizers or sedatives.

7 - The use of tramadol during pregnancy should be avoided.

Because the safety of using tramadol during pregnancy has not been established, the drug should not be used during pregnancy.

Safe use of tramadol in nursing mothers has not been established.

8 - Tramadol is generally well tolerated.
Possible side effects are usually temporary.

Some of the most common side effects associated with tramadol include:
  • Nausea
  • Constipation
  • Mare
  • Headache
  • Drowsiness
  • Vomiting
Less common side effects are itching, sweating, diarrhea, rash, dry mouth and dizziness.
There have been patients who developed seizures after taking tramadol.

9 - A Cochrane review of tramadol for the treatment of osteoarthritis showed a small profit.

The Cochrane said that when tramadol is taken for a maximum of 3 months, there may be decreased pain, improved function and stiffness, and general welfare.However, tramadol can cause side effects that are severe enough to require that the patient should stop taking the medication.
Risks outweigh the benefits for many people who have tried tramadol.

10 - If a tramadol overdose has occurred, call your local poison control center or call 911 if it appears to be an emergency.

Symptoms of overdose include decreased pupil size, difficulty breathing or staying asleep, unconscious, coma, heart attack or a stroke. Call for help, even if you are unsure what to do.




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